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Diamond and carbon nanostructures for biomedical applications

Yuxiang Xue ,
Xue Feng ,
Samuel C. Roberts ,
Xianfeng Chen
Volume 1, Issue 1 (2021)
DOI: 10.1080/26941112.2021.2013716

Abstract

Diamond and carbon nanostructures possess outstanding advantages, such as chemical inertness, stable fluorescence, tunable surface characteristics and excellent biocompatibility. In particular, diamond has extremely strong mechanical properties, and therefore the nanostructures have been developed for unique applications. Herein, we systematically review the very recent applications of these structures in drug delivery, bioimaging and biosensing, followed by discussion of their advantages, limitations and challenges in translation to potential clinical applications and presentation of our insights of their future development.

Keywords

Nanodiamond; diamond; graphene; carbon nanostructures; drug delivery; biosensing

References

  • Gupta T, Gupta T. Historical production and use of carbon materials: the activated carbon. In: Gupta T, editor. Carbon: the black, the gray and the transparent. Cham: Springer; 2018. p. 47–70.
  • Mathur RB, Singh BP, Pande S. Carbon nanomaterials: synthesis, structure, properties and applications. New York: CRC Press; 2016.
  • Falcao EHL, Wudl F. Carbon allotropes: beyond graphite and diamond. J Chem Technol Biotechnol. 2007;82(6):524–531.
  • Hirsch A. The era of carbon allotropes. Nat Mater. 2010;9(11):868–871.
  • Wang Y, Li Z, Wang J, et al. Graphene and graphene oxide: biofunctionalization and applications in biotechnology. Trends Biotechnol. 2011;29(5):205–212.
  • Sankaran KJ, Haenen K. Properties of Carbon Bulk Materials. In Arnault J-C, Eder D, editors. Synthesis and Applications of Nanocarbons. Hoboken: Wiley; 2020. p. 1–23.
  • Kroto HW, Heath JR, O’Brien SC, et al. C 60: buckminsterfullerene. Nature. 1985;318(6042):162–163.
  • Georgakilas V, Perman JA, Tucek J, et al. Broad family of carbon nanoallotropes: classification, chemistry, and applications of fullerenes, carbon dots, nanotubes, graphene, nanodiamonds, and combined superstructures. Chem Rev. 2015;115(11):4744–4822.
  • Li B, Zhao S, Huang L, et al. Recent advances and prospects of carbon dots in phototherapy. Chem Eng J. 2021;408:127245.
  • Li X, Zhao S, Li B, et al. Advances and perspectives in carbon dot-based fluorescent probes: mechanism, and application. Coord Chem Rev. 2021;431:213686.
  • Lan M, Zhang J, Chui Y-S, et al. Carbon nanoparticle-based ratiometric fluorescent sensor for detecting mercury ions in aqueous media and living cells. ACS Appl Mater Interfaces. 2014;6(23):21270–21278.
  • Zhao S, Wu S, Jia Q, et al. Lysosome-targetable carbon dots for highly efficient photothermal/photodynamic synergistic cancer therapy and photoacoustic/two-photon excited fluorescence imaging. Chem Eng J. 2020;388:124212.
  • Chen X, Zhang W. Diamond nanostructures for drug delivery, bioimaging, and biosensing. Chem Soc Rev. 2017;46(3):734–760.
  • Su L-X, Cao Y, Hao H-S, et al. Emerging applications of nanodiamonds in photocatalysis. Funct Diam. 2021;1(1):93–109.
  • Stachel T, Luth RW. Diamond formation – where, when and how? Lithos. 2015;220-223:200–220.
  • Narayan RJ, Boehm RD, Sumant AV. Medical applications of diamond particles & surfaces. Mater Today. 2011;14(4):154–163.
  • Mochalin VN, Shenderova O, Ho D, et al. The properties and applications of nanodiamonds. Nature Nanotech. 2012;7(1):11–23.
  • Narayan J, Bhaumik A. Novel synthesis and properties of pure and NV-doped nanodiamonds and other nanostructures. Mater Res Lett. 2017;5(4):242–250.
  • Dolmatov VY, Myllymäki V, Vehanen A, et al. Dependence of the detonation nanodiamond yield on the detonation process parameters. J Superhard Mater. 2019;41(5):355–359.
  • Shvidchenko AV, Eidelman ED, Vul AY, et al. Colloids of detonation nanodiamond particles for advanced applications. Adv Colloid Interface Sci. 2019;268:64–81.
  • Gorrini F, Cazzanelli M, Bazzanella N, et al. On the thermodynamic path enabling a room-temperature, laser-assisted graphite to nanodiamond transformation. Sci Rep. 2016;6:35244
  • Xiao J, Liu P, Yang GW. Nanodiamonds from coal under ambient conditions. Nanoscale. 2015;7(14):6114–6125.
  • De Feudis M, Tallaire A, Nicolas L, et al. Large‐scale fabrication of highly emissive nanodiamonds by chemical vapor deposition with controlled doping by SiV and GeV centers from a solid source. Adv Mater Interfaces. 2020;7(2):1901408.
  • Basso L, Cazzanelli M, Orlandi M, et al. Nanodiamonds: synthesis and application in sensing, catalysis, and the possible connection with some processes occurring in space. Appl Sci. 2020;10(12):4094.
  • Rehor I, Cigler P. Precise estimation of HPHT nanodiamond size distribution based on transmission electron microscopy image analysis. Diam Relat Mater. 2014;46:21–24.
  • Stehlik S, Varga M, Ledinsky M, et al. Size and purity control of HPHT nanodiamonds down to 1 nm. J Phys Chem C. 2015;119(49):27708–27720.
  • Dideikin AT, Aleksenskii AE, Baidakova MV, et al. Rehybridization of carbon on facets of detonation diamond nanocrystals and forming hydrosols of individual particles. Carbon. 2017;122:737–745.
  • Lu Y, Huang G, Wang S, et al. A review on diamond-like carbon films grown by pulsed laser deposition. Appl Surf Sci. 2021;541:148573.
  • Bakharev PV, Huang M, Saxena M, et al. Chemically induced transformation of chemical vapour deposition grown bilayer graphene into fluorinated single-layer diamond. Nat Nanotechnol. 2020;15(1):59–66.
  • Cumont A, Pitt AR, Lambert PA, et al. Properties, mechanism and applications of diamond as an antibacterial material. Funct Diam. 2021;1(1):1–28.
  • Huang B-R, Wang M-J, Kathiravan D, et al. Interfacial effect of oxygen-doped nanodiamond on CuO and micropyramidal silicon heterostructures for efficient nonenzymatic glucose sensor. ACS Appl Bio Mater. 2018;1(5):1579–1586.
  • Huang F, Deng Y, Chen Y, et al. Anchoring Cu 1 species over nanodiamond-graphene for semi-hydrogenation of acetylene. Nat Commun. 2019;10:4431.
  • Fang J, Wang H, Bao X, et al. Nanodiamond as efficient peroxidase mimic against periodontal bacterial infection. Carbon. 2020;169:370–381.
  • Chen TM, Tian XM, Huang L, et al. Nanodiamonds as pH-switchable oxidation and reduction catalysts with enzyme-like activities for immunoassay and antioxidant applications. Nanoscale. 2017;9(40):15673–15684.
  • Mogilnaya O, Ronzhin N, Artemenko K, et al. Nanodiamonds as an effective adsorbent for immobilization of extracellular peroxidases from luminous fungus neonothopanus nambi to construct a phenol detection system. Biocatal Biotransform. 2019;37(2):97–105.
  • Vaijayanthimala V, Cheng P-Y, Yeh S-H, et al. The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent. Biomaterials. 2012;33(31):7794–7802.
  • van der Laan K, Hasani M, Zheng T, et al. Nanodiamonds for in vivo applications. Small. 2018;14(19):1703838.
  • Chong EYW, Ng CYP, Choi VWY, et al. A diamond nanocone array for improved osteoblastic differentiation. J Mater Chem B. 2013;1(27):3390–3396.
  • Sutisna B, Janssens SD, Giussani A, et al. Block copolymer–nanodiamond coassembly in solution: towards multifunctional hybrid materials. Nanoscale. 2021;13(3):1639–1651.
  • Jariwala DH, Patel D, Wairkar S. Surface functionalization of nanodiamonds for biomedical applications. Mater Sci Eng C. 2020;113:110996.
  • Wei S, Li L, Du X, et al. Off–on nanodiamond drug platform for targeted cancer imaging and therapy. J Mater Chem B. 2019;7(21):3390–3402.
  • Gu M, Toh TB, Hooi L, et al. Nanodiamond-mediated delivery of a G9a inhibitor for hepatocellular carcinoma therapy. ACS Appl Mater Interfaces. 2019;11(49):45427–45441.
  • Gao G, Guo Q, Zhi J. Nanodiamond‐based theranostic platform for drug delivery and bioimaging. Small. 2019;15(48):1902238.
  • Chan MS, Liu LS, Leung HM, et al. Cancer-cell-specific mitochondria-targeted drug delivery by dual-ligand-functionalized nanodiamonds circumvent drug resistance. ACS Appl Mater Interfaces. 2017;9(13):11780–11789.
  • Simon J, Wolf T, Klein K, et al. Hydrophilicity regulates the stealth properties of polyphosphoester‐coated nanocarriers. Angew Chem Int Ed. 2018;57(19):5548–5553.
  • Silva DD, Kaduri M, Poley M, et al. Biocompatibility, biodegradation and excretion of polylactic acid (PLA) in medical implants and theranostic systems. Chem Eng J. 2018;340:9–14.
  • Merz V, Lenhart J, Vonhausen Y, et al. Zwitterion‐functionalized detonation nanodiamond with superior protein repulsion and colloidal stability in physiological media. Small. 2019;15(48):1901551.
  • Madamsetty VS, Pal K, Keshavan S, et al. Development of multi-drug loaded PEGylated nanodiamonds to inhibit tumor growth and metastasis in genetically engineered mouse models of pancreatic cancer. Nanoscale. 2019;11(45):22006–22018.
  • Liao W-S, Ho Y, Lin Y-W, et al. Targeting EGFR of triple-negative breast cancer enhances the therapeutic efficacy of paclitaxel-and cetuximab-conjugated nanodiamond nanocomposite. Acta Biomater. 2019;86:395–405.
  • Yang Y, Yuen M-F, Chen X, et al. Fabrication of arrays of high-aspect-ratio diamond nanoneedles via maskless ECR-assisted microwave plasma etching. CrystEngComm. 2015;17(14):2791–2800.
  • Zhu X, Kwok SY, Yuen MF, et al. Dense diamond nanoneedle arrays for enhanced intracellular delivery of drug molecules to cell lines. J Mater Sci. 2015;50(23):7800–7807.
  • Chen X, Zhu G, Yang Y, et al. A diamond nanoneedle array for potential high‐throughput intracellular delivery. Adv Healthc Mater. 2013;2(8):1103–1107.
  • Zhu X, Yuen MF, Yan L, et al. Diamond‐nanoneedle‐array‐facilitated intracellular delivery and the potential influence on cell physiology. Adv Healthcare Mater. 2016;5(10):1157–1168.
  • He G, Hu N, Xu AM, et al. Nanoneedle platforms: the many ways to pierce the cell membrane. Adv Funct Mater. 2020;30(21):1909890.
  • Zhang Y, Gu Y, He J, et al. Ultrabright gap-enhanced raman tags for high-speed bioimaging. Nat Commun. 2019;10:1–12.
  • Kim D, Jeong K, Kwon JE, et al. Dual-color fluorescent nanoparticles showing perfect color-specific photoswitching for bioimaging and super-resolution microscopy. Nat Commun. 2019;10:1–10.
  • Torelli MD, Nunn NA, Shenderova OA. A perspective on fluorescent nanodiamond bioimaging. Small. 2019;15(48):1902151.
  • Ho D, Wang C-HK, Chow EK-H. Nanodiamonds: the intersection of nanotechnology, drug development, and personalized medicine. Sci Adv. 2015;1(7):e1500439.
  • Fang C, Vaijayanthimala V, Cheng C, et al. The exocytosis of fluorescent nanodiamond and its use as a long‐term cell tracker. Small. 2011;7(23):3363–3370.
  • Alkahtani MH, Alghannam F, Jiang L, et al. Fluorescent nanodiamonds: past, present, and future. Nanophotonics. 2018;7(8):1423–1453.
  • Reineck P, Lau DWM, Wilson ER, et al. Effect of surface chemistry on the fluorescence of detonation nanodiamonds. ACS Nano. 2017;11(11):10924–10934.
  • Shenderova OA, Vlasov II, Turner S, et al. Nitrogen control in nanodiamond produced by detonation shock-wave-assisted synthesis. J Phys Chem C. 2011;115(29):14014–14024.
  • Shenderova OA, Shames AI, Nunn NA, et al. Synthesis, properties, and applications of fluorescent diamond particles. J Vac Sci Technol B Nanotechnol Microelectron Mater Process Meas Phenom. 2019;37:30802.
  • Morita M, Tachikawa T, Seino S, et al. Controlled synthesis of gold nanoparticles on fluorescent nanodiamond via electron-beam-induced reduction method for dual-modal optical and electron bioimaging. ACS Appl Nano Mater. 2018;1(1):355–363.
  • Yoshino F, Amano T, Zou Y, et al. Preferential tumor accumulation of polyglycerol functionalized nanodiamond conjugated with cyanine dye leading to near‐infrared fluorescence in vivo tumor imaging. Small. 2019;15(48):1901930.
  • Lila ASA, Nawata K, Shimizu T, et al. Use of polyglycerol (PG), instead of polyethylene glycol (PEG), prevents induction of the accelerated blood clearance phenomenon against long-circulating liposomes upon repeated administration. Int J Pharm. 2013;456(1):235–242.
  • Choi HS, Liu W, Misra P, et al. Renal clearance of nanoparticles. Nat Biotechnol. 2007;25(10):1165–1170.
  • Hoshyar N, Gray S, Han H, et al. The effect of nanoparticle size on in vivo pharmacokinetics and cellular interaction. Nanomedicine. 2016;11(6):673–692.
  • Gobet J, Volpe P-N, Dubois M-A. Friction coefficient of diamond under conditions compatible with microelectromechanical systems applications. Appl Phys Lett. 2016;108(12):124103.
  • Shuai C, Li Y, Wang G, et al. Surface modification of nanodiamond: toward the dispersion of reinforced phase in poly-l-lactic acid scaffolds. Int J Biol Macromol. 2019;126:1116–1124.
  • Morimune-Moriya S, Yada S, Kuroki N, et al. Strong reinforcement effects of nanodiamond on mechanical and thermal properties of polyamide 66. Compos Sci Technol. 2020;199:108356.
  • Zhang F, Song Q, Huang X, et al. A novel high mechanical property PLGA composite matrix loaded with nanodiamond–phospholipid compound for bone tissue engineering. ACS Appl Mater Interfaces. 2016;8(2):1087–1097.
  • Feng P, Kong Y, Yu L, et al. Molybdenum disulfide nanosheets embedded with nanodiamond particles: co-dispersion nanostructures as reinforcements for polymer scaffolds. Appl Mater Today. 2019;17:216–226.
  • Novoselov KS, Geim AK, Morozov SV, et al. Electric field effect in atomically thin carbon films. Science (80. 2004;306(5696):666–669.
  • Kumar R, Sahoo S, Joanni E, et al. Heteroatom doped graphene engineering for energy storage and conversion. Mater Today. 2020;39:47–65.
  • Yang W, He C, Zhang L, et al. Growth, characterization, and properties of nanographene. Small. 2012;8(9):1429–1435.
  • Han P, Yao X, Müllen K, et al. Size-dependent electron transfer from atomically defined nanographenes to metal oxide nanoparticles. Nanoscale. 2020;12(30):16046–16052.
  • Chen L, Hernandez Y, Feng X, et al. From nanographene and graphene nanoribbons to graphene sheets: chemical synthesis. Angew Chem Int Ed. 2012;51(31):7640–7654.
  • Jassas RS, Mughal EU, Sadiq A, et al. Scholl reaction as a powerful tool for the synthesis of nanographenes: a systematic review. RSC Adv. 2021;11(51):32158–32202.
  • Vo TH, Shekhirev M, Kunkel DA, et al. Bottom-up solution synthesis of narrow nitrogen-doped graphene nanoribbons. Chem Commun. 2014;50(32):4172–4174.
  • Tan Y-Z, Yang B, Parvez K, et al. Atomically precise edge chlorination of nanographenes and its application in graphene nanoribbons. Nat Commun. 2013;4:2646.
  • Fujii S, Enoki T. Nanographene and graphene edges: electronic structure and nanofabrication. Acc Chem Res. 2013;46(10):2202–2210.
  • Manrique DZ, You JW, Deng H, et al. Quantum plasmon engineering with interacting graphene nanoflakes. J Phys Chem C. 2017;121(49):27597–27602.
  • Banerjee S, Bhattacharyya D. Electronic properties of nano-graphene sheets calculated using quantum chemical DFT. Comput Mater Sci. 2008;44(1):41–45.
  • Robertson NM, Toscano AE, LaMantia VE, et al. Unlocked nucleic acids for miRNA detection using two dimensional nano-graphene oxide. Biosens Bioelectron. 2017;89:551–557.
  • Qi L, Fan Y-Y, Wei H, et al. Graphene oxide-enhanced and proflavine-probed fluorescence polarization biosensor for ligand-RNA interaction assay. Sensors Actuators B Chem. 2018;257:666–671.
  • Sanchez VC, Jachak A, Hurt RH, et al. Biological interactions of graphene-family nanomaterials: an interdisciplinary review. Chem Res Toxicol. 2012;25(1):15–34.
  • Liu J, Cui L, Losic D. Graphene and graphene oxide as new nanocarriers for drug delivery applications. Acta Biomater. 2013;9(12):9243–9257.
  • Ashraf MA, Peng W, Zare Y, et al. Effects of size and aggregation/agglomeration of nanoparticles on the interfacial/interphase properties and tensile strength of polymer nanocomposites. Nanoscale Res Lett. 2018;13(1):214.
  • Lee C, Wei X, Kysar JW, et al. Measurement of the elastic properties and intrinsic strength of monolayer graphene. Science. 2008;321(5887):385–388.
  • Georgakilas V, Tiwari JN, Kemp KC, et al. Noncovalent functionalization of graphene and graphene oxide for energy materials, biosensing, catalytic, and biomedical applications. Chem Rev. 2016;116(9):5464–5519.
  • Pérez EM, Martín N. π–π interactions in carbon nanostructures. Chem Soc Rev. 2015;44(18):6425–6433.
  • Xiao F, Chen Z, Wei Z, et al. Hydrophobic interaction: a promising driving force for the biomedical applications of nucleic acids. Adv Sci. 2020;7(16):2001048.
  • Sasidharan A, Panchakarla LS, Chandran P, et al. Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene. Nanoscale. 2011;3(6):2461–2464.
  • Gao W, Alemany LB, Ci L, et al. New insights into the structure and reduction of graphite oxide. Nature Chem. 2009;1(5):403–408.
  • Marcano DC, Kosynkin DV, Berlin JM, et al. Improved synthesis of graphene oxide. ACS Na. 2010;4(8):4806–4814.
  • Jain VP, Chaudhary S, Sharma D, et al. Advanced functionalized nanographene oxide as a biomedical agent for drug delivery and anti-cancerous therapy: a review. Eur Polym J. 2021;142:110124.
  • Wang A, Yu W, Huang Z, et al. Covalent functionalization of reduced graphene oxide with porphyrin by means of diazonium chemistry for nonlinear optical performance. Sci Rep. 2016;6:23325.
  • Yu W, Sisi L, Haiyan Y, et al. Progress in the functional modification of graphene/graphene oxide: a review. RSC Adv. 2020;10(26):15328–15345.
  • Hermanson GT. Bioconjugate techniques. London, Waltham, and San Diego: Academic Press; 2013.
  • Hutchins KM. Functional materials based on molecules with hydrogen-bonding ability: applications to drug co-crystals and polymer complexes. R Soc Open Sci. 2018;5(6):180564.
  • Liu Z, Robinson JT, Sun X, et al. PEGylated nanographene oxide for delivery of water-insoluble cancer drugs. J Am Chem Soc. 2008;130(33):10876–10877.
  • Mugnano M, Lama GC, Castaldo R, et al. Cellular uptake of mildly oxidized nanographene for drug-delivery applications. ACS Appl Nano Mater. 2020;3(1):428–439.
  • Li S, Zheng J, Chen D, et al. Yolk–shell hybrid nanoparticles with magnetic and pH-sensitive properties for controlled anticancer drug delivery. Nanoscale. 2013;5(23):11718–11724.
  • Depan D, Shah J, Misra RDK. Controlled release of drug from folate-decorated and graphene mediated drug delivery system: synthesis, loading efficiency, and drug release response. Mater Sci Eng C. 2011;31(7):1305–1312.
  • Sun X, Liu Z, Welsher K, et al. Nano-graphene oxide for cellular imaging and drug delivery. Nano Res. 2008;1(3):203–212.
  • Vaidyanathan S, Chen J, Orr BG, et al. Cationic polymer intercalation into the lipid membrane enables intact polyplex DNA escape from endosomes for gene delivery. Mol Pharm. 2016;13(6):1967–1978.
  • Oskuee RK, Dabbaghi M, Gholami L, et al. Investigating the influence of polyplex size on toxicity properties of polyethylenimine mediated gene delivery. Life Sci. 2018;197:101–108.
  • Ahn HH, Lee MS, Cho MH, et al. DNA/PEI nano-particles for gene delivery of rat bone marrow stem cells. Colloids Surfaces A Physicochem Eng Asp. 2008;313-314:116–120.
  • Godbey WT, Wu KK, Mikos AG. Size matters: molecular weight affects the efficiency of poly (ethylenimine) as a gene delivery vehicle. J Biomed Mater Res. 1999;45(3):268–275.
  • Imani R, Prakash S, Vali H, et al. Polyethylene glycol and octa-arginine dual-functionalized nanographene oxide: an optimization for efficient nucleic acid delivery. Biomater Sci. 2018;6(6):1636–1650.
  • Chertok B, David AE, Yang VC. Polyethyleneimine-modified iron oxide nanoparticles for brain tumor drug delivery using magnetic targeting and intra-carotid administration. Biomaterials. 2010;31(24):6317–6324.
  • Zhu J, Tang A, Law LP, et al. Amphiphilic core-shell nanoparticles with poly (ethylenimine) shells as potential gene delivery carriers. Bioconjugate Chem. 2005;16(1):139–146.
  • Feng L, Zhang S, Liu Z. Graphene based gene transfection. Nanoscale. 2011;3(3):1252–1257.
  • Zhang L, Lu Z, Zhao Q, et al. Enhanced chemotherapy efficacy by sequential delivery of siRNA and anticancer drugs using PEI‐grafted graphene oxide. Small. 2011;7(4):460–464.
  • Yang H-W, Huang C-Y, Lin C-W, et al. Gadolinium-functionalized nanographene oxide for combined drug and microRNA delivery and magnetic resonance imaging. Biomaterials. 2014;35(24):6534–6542.
  • Zhao H, Ding R, Zhao X, et al. Graphene-based nanomaterials for drug and/or gene delivery, bioimaging, and tissue engineering. Drug Discov Today. 2017;22(9):1302–1317.
  • Ovsianikov A, Khademhosseini A, Mironov V. The synergy of scaffold-based and scaffold-free tissue engineering strategies. Trends Biotechnol. 2018;36(4):348–357.
  • Goenka S, Sant V, Sant S. Graphene-based nanomaterials for drug delivery and tissue engineering. J Control Release. 2014;173:75–88.
  • Shin SR, Li Y-C, Jang HL, et al. Graphene-based materials for tissue engineering. Adv Drug Deliv Rev. 2016;105:255–274.
  • Wu D, Samanta A, Srivastava RK, et al. Starch-derived nanographene oxide paves the way for electrospinnable and bioactive starch scaffolds for bone tissue engineering. Biomacromolecules. 2017;18(5):1582–1591.
  • Yadav A, Erdal NB, Hakkarainen M, et al. Cellulose-derived nanographene oxide reinforced macroporous scaffolds of high internal phase emulsion-templated cross-Linked poly (ε-caprolactone). Biomacromolecules. 2020;21(2):589–596.
  • Jo SB, Erdenebileg U, Dashnyam K, et al. Nano-graphene oxide/polyurethane nanofibers: mechanically flexible and myogenic stimulating matrix for skeletal tissue engineering. J Tissue Eng. 2020;11:204173141990042.
  • McCaul M, Glennon T, Diamond D. Challenges and opportunities in wearable technology for biochemical analysis in sweat. Curr Opin Electrochem. 2017;3(1):46–50.
  • Ferreira JJ, Fernandes CI, Rammal HG, et al. Wearable technology and consumer interaction: a systematic review and research agenda. Comput Hum Behav. 2021;118:106710.
  • Wu Z-S, Tan Y-Z, Zheng S, et al. Bottom-up fabrication of sulfur-doped graphene films derived from sulfur-annulated nanographene for ultrahigh volumetric capacitance micro-supercapacitors. J Am Chem Soc. 2017;139(12):4506–4512.
  • Zhang C, Kang T-H, Yu J-S. Three-dimensional spongy nanographene-functionalized silicon anodes for lithium ion batteries with superior cycling stability. Nano Res. 2018;11(1):233–245.
  • Wu Q, Xie D-J, Zhang Y-D, et al. Mechanical properties and simulation of nanographene/polyvinylidene fluoride composite films. Compos Part B Eng. 2019;156:148–155.
  • Liu X, Liu D, Lee J, et al. Spider-web-inspired stretchable graphene woven fabric for highly sensitive, transparent, wearable strain sensors. ACS Appl Mater Interfaces. 2019;11(2):2282–2294.
  • Romero FJ, Castillo E, Rivadeneyra A, et al. Inexpensive and flexible nanographene-based electrodes for ubiquitous electrocardiogram monitoring. npj Flex Electron. 2019;3:12.
  • Toh C-T, Zhang H, Lin J, et al. Synthesis and properties of free-standing monolayer amorphous carbon. Nature. 2020;577(7789):199–203.
  • Bhattarai B, Pandey A, Drabold DA. Evolution of amorphous carbon across densities: an inferential study. Carbon. 2018;131:168–174.
  • Bhattarai B, Drabold DA. Amorphous carbon at low densities: an ab initio study. Carbon. 2017;115:532–538.
  • Xiong Y, Schneider J, Ushakova EV, et al. Influence of molecular fluorophores on the research field of chemically synthesized carbon dots. Nano Today. 2018;23:124–139.
  • Nufer S, Fantanas D, Ogilvie SP, et al. Percolating metallic structures templated on laser-deposited carbon nanofoams derived from graphene oxide: applications in humidity sensing. ACS Appl Nano Mater. 2018;1(4):1828–1835.
  • Li X, Zhao L, Li P, et al. In-situ electron microscopy observation of electrochemical sodium plating and stripping dynamics on carbon nanofiber current collectors. Nano Energy. 2017;42:122–128.
  • Li X, Zhang D, Xu X, et al. Tailoring the nanostructure of graphene as an oil-based additive: toward synergistic lubrication with an amorphous carbon film. ACS Appl Mater Interfaces. 2020;12(38):43320–43330.
  • Zhao T, Ji X, Jin W, et al. Electromagnetic wave absorbing properties of aligned amorphous carbon nanotube/BaFe12O19 nanorod composite. J Alloys Compd. 2017;703:424–430.
  • Yoo K, Miller B, Kalish R, et al. Electrodes of nitrogen‐incorporated tetrahedral amorphous carbon a novel thin‐film electrocatalytic material with diamond‐like stability. Electrochem Solid-State Lett. 1999;2(5):233.
  • Palomäki T, Peltola E, Sainio S, et al. Unmodified and multi-walled carbon nanotube modified tetrahedral amorphous carbon (ta-C) films as in vivo sensor materials for sensitive and selective detection of dopamine. Biosens Bioelectron. 2018;118:23–30.
  • Peltola E, Wester N, Holt KB, et al. Nanodiamonds on tetrahedral amorphous carbon significantly enhance dopamine detection and cell viability. Biosens Bioelectron. 2017;88:273–282.
  • Field SK, Jarratt M, Teer DG. Tribological properties of graphite-like and diamond-like carbon coatings. Tribol Int. 2004;37(11-12):949–956.
  • Dong D, Jiang B, Li H, et al. Effect of graphite target power density on tribological properties of graphite-like carbon films. Appl Surf Sci. 2018;439:900–909.
  • Zhu H, Hassan T, Kabir H, et al. Voltammetric pH sensor based on electrochemically modified pseudo-graphite. Analyst. 2020;145(22):7252–7259.
  • Zhang X, Yu X, Wen K, et al. Multiplex lateral flow immunoassays based on amorphous carbon nanoparticles for detecting three fusarium mycotoxins in maize. J Agric Food Chem. 2017;65(36):8063–8071.
  • Moyano A, Serrano-Pertierra E, Salvador M, et al. Carbon-Coated superparamagnetic nanoflowers for biosensors based on lateral flow immunoassays. Biosensors. 2020;10(8):80.
  • Hu Y, Domínguez CM, Bauer J, et al. Carbon-nanotube reinforcement of DNA-silica nanocomposites yields programmable and cell-instructive biocoatings. Nat Commun. 2019;10(1):5522
  • Sobolev A, Valkov A, Kossenko A, et al. Bioactive coating on Ti alloy with high osseointegration and antibacterial Ag nanoparticles. ACS Appl Mater Interfaces. 2019;11(43):39534–39544.
  • Kapat K, Shubhra QTH, Zhou M, et al. Piezoelectric nano‐biomaterials for biomedicine and tissue regeneration. Adv Funct Mater. 2020;30(44):1909045.
  • Granek A, Monika M, Ozimina D. Diamond-like carbon films for use in medical implants. AIP Conf Proc. 2018;2017:020006.
  • Hajduga MB, Bobinski R. TiN, ZrN and DLC nanocoatings-a comparison of the effects on animals, in-vivo study. Mater Sci Eng C. 2019;104:109949.
  • Hauert R, Thorwarth K, Thorwarth G. An overview on diamond-like carbon coatings in medical applications. Surf Coatings Technol. 2013;233:119–130.
  • Choudhury D, Lackner J, Fleming RA, et al. Diamond-like carbon coatings with zirconium-containing interlayers for orthopedic implants. J Mech Behav Biomed Mater. 2017;68:51–61.
  • Cloutier M, Mantovani D, Rosei F. Antibacterial coatings: challenges, perspectives, and opportunities. Trends Biotechnol. 2015;33(11):637–652.
  • Glinel K, Thebault P, Humblot V, et al. Antibacterial surfaces developed from bio-inspired approaches. Acta Biomater. 2012;8(5):1670–1684.
  • Yonezawa K, Kawaguchi M, Kaneuji A, et al. Evaluation of antibacterial and cytotoxic properties of a fluorinated diamond-like carbon coating for the development of antibacterial medical implants. Antibiotics. 2020;9(8):495.
  • Chipaux M, van der Laan KJ, Hemelaar SR, et al. Nanodiamonds and their applications in cells. Small. 2018;14(24):1704263.
  • Li Y, Feng L, Shi X, et al. Surface coating‐dependent cytotoxicity and degradation of graphene derivatives: towards the design of non‐toxic, degradable nano‐graphene. Small. 2014;10(8):1544–1554.