Recent applications of fluorescent nanodiamonds containing nitrogen-vacancy centers in biosensing

Yuchen Feng; Qi Zhao; Yuxi Shi; Guanyue Gao; Jinfang Zhi

doi:10.1080/26941112.2022.2153233

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Recent applications of fluorescent nanodiamonds containing nitrogen-vacancy centers in biosensing

Review | Updated：2022-12-10

- Recent applications of fluorescent nanodiamonds containing nitrogen-vacancy centers in biosensing
- Functional Diamond Vol. 2, Issue 1, Pages: 192-203(2022)
- Affiliations：
  
  1. a Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing PR China
  2. b University of Chinese Academy of Sciences
  3. a Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and Chemistry Chinese Academy of Sciences
- Author bio：
- Funds：
- DOI：10.1080/26941112.2022.2153233
  CLC：
- Online First：10 December 2022，
  
  Published：2022
- Accepted：
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Yuchen Feng, Qi Zhao, Yuxi Shi, et al. Recent applications of fluorescent nanodiamonds containing nitrogen-vacancy centers in biosensing[J]. Functional Diamond2022, 2(1): 192-203.
DOI：

Yuchen Feng, Qi Zhao, Yuxi Shi, et al. Recent applications of fluorescent nanodiamonds containing nitrogen-vacancy centers in biosensing[J]. Functional Diamond2022, 2(1): 192-203. DOI： 10.1080/26941112.2022.2153233.

摘要

Abstract

Fluorescent nanodiamonds (FNDs) with nitrogen-vacancy (NV) centers have been extensively studied in numerous fields because of their distinct magneto-optical properties. The NV center is a perfect candidate for a nanosensor because of its stable photoluminescence and manipulable spin state by microwave/magnetic field. Considering the controllable sizes (5–100 nm)

abundant surface groups

and good biocompatibility

FNDs are valuable in biosensing to study the physiological activity at the cellular scale. This review summarizes the recent applications of FNDs in detecting physiological parameters (such as temperature

pH) as well as proteins

free radicals

viruses

etc. Highlights include the development of FND-based biosensors and the NV center transduction system that responds to signal changes or concentrations fluctuations of target species.

关键词

Keywords

references

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